Browsing UFR des Sciences et Technologies (ST) by Author "Gassama, Abdoulaye"
Now showing items 21-38 of 38
-
Isolation, chemical characterization, evaluation of analgesic and anti-inflammatory activities of triterpenoids from the tubers of raphionacme vignei E. A. Bruce (Apocynaceae)
Diatta, Diara; Camara, Mamadou Fodé; Sène, Madièye; Yao-Kouassi, Philomène akoua; Barboza, Firmin Sylva; Gassama, Abdoulaye; Lavaud, Catherine; Sy, Gata Yoro (2021)Raphionacme vignei E. A. Bruce (Apocynaceae) is a plant of the traditional African pharmacopoeia, whose parts are used in the treatment of various pathologies. Water-soaked R. vignei tubers are edible. The objective of ... -
Isolation, structural determination and anti-hyperglycemic effect of dietthyl terephthalate extracted from the leaves of Dalium guineense (Caesalpiniaceae)
Diassy, Henry; Diatta, Charlot; Barboza, Firmin Sylva; Ball, Fatimata Seydy; Sow, Marie; Dione, El Hadji; Gassama, Abdoulaye; Sy, Gata Yoro (2023)Previous work had demonstrated the lack of hypoglycemic effect of the butanol-ethyl acetate fraction (BEAF) of the leaves of Dialium Guineense (Caesalpiniaceae). However, this same fraction is anti-hyperglycemic in ... -
Photochemical Electron Transfer Mediated Addition of Naphthylamine Derivatives to Electron-Deficient Alkenes
Jahjah, Rabih; Gassama, Abdoulaye; Dumur, Frédéric; Richert, Sabine; Landgraf, Stephan; Lebrun, Aurélien; Cadiou, Cyril; Sellès, Patrice; Marinkovic, Sinisa (2011): Using photochemical electron transfer, N,N-dimethylnaphthylamine derivatives are added to R,β-unsaturated carboxylates. The addition takes place exclusively in the Rposition of electron-deficient alkenes and mainly in ... -
Photochemical Key Steps in thé Synthesis of Surfactants from Furfural-Derived Intermediates
Ernenwein, Cédric; Gassama, Abdoulaye; Hoffmann, Norbert (Elsevier, 2009)Le furfural est oxydé en 2 [5H] -furanone en utilisant du peroxyde d'hydrogène ou à la 5-hydroxy-2 [5H] -furanone par photo-oxygénation. Une fonction aminé est introduite par ajout radical d'aminés tertiaires, dont ... -
Regioselective Annulation of 1,5-Diketones: Access to Functionalized Hagemann’s Esters
Gassama, Abdoulaye; Angelo, Jean d'; Cavé, Christian; Mahuteau, Jacqueline; Riche, Claude; (European Journal of Organic Chemistry, 2000)The synthesis of the ‘‘functionalized’’ Hagemann’s ester (S)- 18 was investigated. The common starting material in these approaches was enamino ester (S,Z)-5, which was prepared through the condensation of keto diester ... -
Selective Light Supported Oxidation of Hexoses Using Air as Oxidant – Synthesis of Tetrahydroxyazepanes
Gassama, Abdoulaye; Offmann, Norbert (2007)Les alkyl glycosides non protégés ont été oxydé avec de l'air comme oxydant et du chlorure de cuivre (I) / TEMPO comme système catalytique. Le primaire le groupe hydroxy en position 6 est sélectivement transformé en un ... -
Stereoselective Triplet-Sensitised Radical Reactions of Furanone Derivatives
Jahjah, Rabih; Gassama, Abdoulaye; Bulach, Véronique; Suzuki, Chikako; Abe, Manabu; Hoffmann, Norbert; Martinez, Agathe; Nuzillard, Jean-Marc (2010)The stereo- and regioselectivity of triplet-sensitised radical reactions of furanone derivatives have been investigated. Furanones 7 a,b were excited to the 3 pp* state by triplet energy transfer from acetone. Intramolecular ... -
Structural determination of news flavones C-glycosides and trans (S, E)- (-) clovamide isolated Icacina senegalensis Juss leaves (Icacinaceae)
Manga, Anastasie; Gassama, Abdoulaye; Sy, Gata Yoro; Bassène, Emmanuel; Lavaud, Cathérine (2013)Les jeunes feuilles de Icacina senegalensis Juss (Icacinaceae) récoltées en février 2012 dans l’enceinte de l’Université Assaue Seck de Ziguinchor (Sénégal) sont mis en décotion pendant 4heures dans des solvants de ... -
Sulfonated surfactants obtained from furfural
Gassama, Abdoulaye; Ernenwein, Cédric; Youssef, Ali; Agach, Mickaël; Riguet, Emmanuel; Marinkovic, Sinisa; Estrine, Boris; Hoffmann, Norbert (2013)Furfural obtained from pentose containing biomass such as hemicelluloses is subjected to photooxygenation. The resulting hydroxyfuranone obtained in high yields undergoes acetalization with fatty alcohols. Using NaHSO3, ... -
Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives
Seck, Rokhyatou; Gassama, Abdoulaye; Cojean, Sandrine; Cavé, Christian (2020)In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and with a less side-effects, we have designed and synthesized a library of 1,4-disubstituted piperidine derivatives from 4-aminopiperidine ... -
Synthesis and antimalarial activity of cinnamic acid derivatives
Seck, Rokhyatou; Mansaly, Malamine; Gassama, Abdoulaye; Cavé, Christian; Cojean, Sandrine (2019)A peptide coupling reaction between 1-(R)-phenylethylalanine and cinnamic acid derivatives has been successfully employed for the synthesis of a set of small molecules. The antimalarial activity of these derivative molecules ... -
Synthesis and characterization of regioselectively monoderivatized maltooligosaccharides through a combination of tandem mass spectrometry and enzymatic hydrolysis studies
Gassama, Abdoulaye; Lesur, David; Brique, Arnaud; Thiebault, Nicolas; Djedaïni-Pilard, Florence; Pilard, Serge; Moreau, Vincent (2013)Recently, we have designed chemical strategies leading to C-6 perfunctionalized linear maltoheptaose derivatives via the acetolysis of persubstituted β-cyclodextrin (β-CD) at the 6-positions. This approach has now been ... -
Synthesis and evaluation of the antimalarial activity of cinnamic acids derived from piperidine
Seck, Rokhyatou; Mansaly, Malamine; Gassama, Abdoulaye; Cavé, Christian; Cojean, Sandrine (2019)The synthesis and antimalarial activity of 1, 4-aminopiperidine derived cinnamic acids are described. Different analogs are prepared from reductive amination reactions and SN1 substitutions. These analogs are tested ... -
Synthesis of 1,2,3-triazole containing derivative of peperidine
Thiam, Aminata; Seck, Rokhyatou; Camara, Magatte; Sambou, Oumar; Diatta, Armel; Gassama, Abdoulaye (2020)A reductive amination reaction between N-Boc -piperidin-4-one and phenoxy-ethylamine was successfully used for the synthesis of (5-Methyl-2-phenyl-2H-[1,2,3] triazol-4ylmethyl)- (2-phenoxy-ethyl)-piperidin-4-yl-amine. The ... -
Synthesis of N-Substituted piperidines from piperidone
Gassama, Abdoulaye; Diatta, Armel (2015)A reductive amination reaction between N-boc-piperidin-4-one and 3,4-dichloroaniline was successfully employed for the synthesis of the N-(3,4-dichloropheny)-N-(2-phenoxylethyl) piperidin-4-amine. The synthesis of a small ... -
Synthesis of regioselectively and uniformly modified maltoheptaose derivatives from cyclomaltoheptaose precursors
Lesur, David; Gassama, Abdoulaye; Moreau, Vincent; (Elsevier, 2005)Dérivés de l'heptadeoxy-6I – VII-halo, -azido et de l'hepta-6I – VII S-hepta (N-Boc-2-amino) éthyl-6I – VII-heptathiomaltoheptaose ont été préparés par acétolyse des dérivés de b-cyclodextrine modifiés par la per-C-6 ... -
Synthesis of surfactants from furfural derived 2[5H]-furanone and fatty amines
Gassama, Abdoulaye; Ernenwein, Cedric; Hoffmann, Norbert (2010)Furfural was oxidized to 2[5H]-furanone 2 using hydrogen peroxide. Furanone 2 was transformed with two equivalents of fatty amines. A condensation and a Michael reaction occurred. Ethyl bromoacetate 5 or methyl acrylate ... -
Synthèse de ligands organiques par réaction de condensation et par réaction catalysée par Gd et Nd. détermination de structure par spectroscopie et par diffraction des rayons X.
Gaye, M.; Sall, A. Salam; Tamboura, F. B.; Diouf, O.; Gassama, Abdoulaye; Pontillon, Y. (2002)The reaction of condensation between hydrazide and aldehyde allowed the formation of compounds 1.2 and 3. The compounds 3 can also be synthesized from 1 or 2 in the presence of Ln...