Synthesis of 1,2,3-triazole containing derivative of peperidine

Abstract

A reductive amination reaction between N-Boc -piperidin-4-one and phenoxy-ethylamine was successfully used for the synthesis of (5-Methyl-2-phenyl-2H-[1,2,3] triazol-4ylmethyl)- (2-phenoxy-ethyl)-piperidin-4-yl-amine. The total synthesis of this small molecule is reported for the first time in this study.