Browsing by Author "Gassama, Abdoulaye"
Now showing items 1-20 of 38
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2,6-Quinolinyl dérivatives as potent VLA-4 antagonistes
Lassoie, Marie-Agnès; Gassama, Abdoulaye; Broeders, Fabienne; Collart, Phillippe (Elsevier, 2007)Une nouvelle série de dérivés 2,6-quinolinyle a été préparée conduisant à de puissants antagonistes de VLA-4 / VCAM-1 nanomolaires puissants. -
Activité Anti-Hyperglycémiante Et Élucidation Structurale Des Composés Isolés Des Feuilles De Spondias Purpurea L. (Anacardiaceae)
Diatta, Armel; Manga, Anastasie; Gassama, Abdoulaye; Lavaud, Catherine (2017)Spondias purpurea L. (Anacardiaceae) is a Senegalese traditional pharmacopoeia plant, which leaves are used in the treatment of various diseases. The leaves’ ethanolic extract exhibited antihyperglycemic activity on ... -
Analgesic and Anti-inflammatory Activities of Triterpenoid Molecules Isolated from the Leaves of Combretum glutinosum Perr. Ex DC (Combretaceae)
Séne, Madièye; Ndiaye, Daouda; Gassama, Abdoulaye; Barboza, Firmin Sylva; Mbaye, Mbaye Diagne; Sy, Gata Yoro (2018)Combretum glutinosum Perr. Ex DC (COMBRETACEAE) is a traditional medicinal plant, widely distributed in Senegal and Africa. The aim of that study was to investigate the analgesic and antiinflammatory activities of two ... -
Antimicrobial anthraquinones and triterpenoid isolated from Morinda geminata DC (Rubiaceae)
Gassama, Abdoulaye; Sambou, Oumar; Karé, Moussa; Gambe, Dame; Rivard, Michael; Martens, Thierry; Lachaise, Isabelle (2017)Morinda geminata DC is a plant of the traditional Senegalese pharmacopoeia, the leaves of which are used in the treatment of various diseases. The phytochemical investigation of its leaves and roots resulted in the isolation ... -
Antiplasmodial activity of extracts of Khaya senegalensis (Ders.) A. Jus (Meliaceae) and Melia azedarach L., plants of senegalese traditional medecine
Manga, Anastasie; Gassama, Abdoulaye; Diatta, K.; Bassène, Emmanuel; Cojean, Serge; Cavé, Christian (2018)Two medicinal plants (Khaya senegalensis and Melia azedarach), frequently used by a large part of the Senegalese population and in particular that of the natural region of Casamance in the traditional treatment of ... -
Antiplasmodial activity of the ethanolic extract of icacina oliviformis (STEMS), spondias purpurea L.(leaves, barks and roots) and cocos nucifera L. (coconut shell fibers) from Ziguinchor, Senegal
Diatta, Armel; Sambou, Oumar; Gassama, Abdoulaye; Cojean, Sandrine; Cavé, Christian (2018)Icacina oliviformis (poiret) Raynal (Icacinaceae), Spondias purpurea L. (Anacardiaceae) and Cocos nucifera L. (Arecaceae) are Senegalese traditional pharmacopoeia plants used in the treatment of various diseases. These plants ... -
Asymmetric synthesis of glutamate derivatives
Seck, Rokhyatou; Gassama, Abdoulaye; Nour, Mohammed; Demange, Luc; Cavé, Christian (2017)Analogs of glutamic acid were synthesized through the asymmetric Michael reaction using chiral acyclic E-enaminoesters and various Michael acceptors. The influence of the alkoxy group of the enaminoesters and also the ... -
Case of Charge-Assisted Hydrogen Bonding in the Crystal Structure of Sodium Laurate, Lauric Acid
Goudiaby, Ibrahima; Guillot, Benoît; Wenger, Emmanuel; Soudani, Sarra; Ben Nasr, Cherif; Camara, Magatte; Gassama, Abdoulaye; Jelsch, Christian (2022)Crystals of Sodium Laurate, Lauric Acid (NaLLA) were obtained and the structure was determined by single-crystal X-ray difraction. The new crystal form is monoclinic of space group P21/c. The asymmetric unit contains two ... -
Condensation of Chiral lmines and Chiral ]]-Enaminoesters with Maleic and Citraconic Anhydrides
Gassama, Abdoulaye; Cavé, Christian; Mahuteau, Jacqueline; Angelo, Jean d'; Riche, Claude (1997)Condenmlions of chiral imines I and 4, and chiral ennminoesters 10 and 13. ~ ma/e~ and citracoaic anhydrides were reported. These experimen:al om~com~ can be ratio _l~__~ed by invaking the compact, eado-aplaroaches of ... -
Détermination structurale de triterpenoïdes isolés des feuilles de Combretum glutinosium Perr. Ex DC (Combretaceae)
Ndiaye, Daouda; Mbaye, Mbaye Diagne; Gassama, Abdoulaye; Lavaud, Catherine; Pilard, Serge (2017)Combretum glutinosum Perr.Ex DC est une plante de la pharmacopée traditionnelle sénégalaise dont les feuilles sont utilisées dans le traitement de diverses maladies. Quatre triterpénoïdes bétulinol 1, bétulonal 2, acide ... -
Diastereoselective Addition of Organomagnesium and Organolithium Reagents to Chiral Trifluoromethyl N-tert-Butanesulfinyl Hemiaminals
Grellepois, Fabienne; Ben Jamaa, Abdelkhalek; Gassama, Abdoulaye (2013)The asymmetric synthesis of trifluoromethylated tertiary and secondary carbinamines (α,α-dibranched and α-branched amines) was achieved by reaction of alkyl, aryl and allyl organomagnesium or organolithium reagents to ... -
Dinuclear zinc complexes using a set of two polytadenate phenolate ligands and applications in polymerization of catalysis of D,L-Lactone
Faye, Djiby; Mbaye, Mbaye Diagne; Gassama, Abdoulaye; Dieng, Samba Yande (2021)The synthesis and characterization of 9 dinuclear zinc complexes are reported, including the X-ray crystal structures of 5 complexes. The set of three ligand motif (R) -2,6-bis((E) -((2-(dimethylamino) ethyl) imino) methyl) ... -
Effects on Blood Glucose of Ethyl Acetate-Butanol Fraction of Dialium guineense Aqueous Leaf Extract (Cesalpiniaceae)
Diatta, Charlot; Diassy, Henry; Barboza, Firmin Sylva; Ball, Fatimata Seydy; Camara, Mariama; Gassama, Abdoulaye; Sy, Gata Yoro (2022)Introduction: The overall objective of the study was to evaluate the effect on blood glucose of the ethyl acetate-butanol fraction (EABF) compounds of the aqueous leaf extract of Dialium guineense (Cesalpiniaceae). Materials ... -
Electrospray ionization mass spectrometry: a key analytical tool for the characterization of regioselectively derivatized maltooligosaccharides obtained starting from natural b-cyclodextrin
Lesur, David; Gassama, Abdoulaye; Moreau, Vincent; Djedaïni-Pilard, Florence; Brique, Arnaud; Pilard, Serge (Published online in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/rcm.2369, 2006)The development of natural cyclodextrins (CDs) for various industrial applications (agroalimentary, cosmetic or pharmaceutical) constitutes a continuous challenge. For the integration of these agricultural plant products ... -
Enantioselective acces to five- and six- membered nitogen - containing heterocycles, based on the asymetric Michael addition of chiral imines and chiral enamino esters.
Angelo, Jean d'; Cavé, Christian; Gassama, Abdoulaye; Desmaële, Didier; Thominiaux, Cyrille; Riche, Claude (1998)The addition reaction of chiral imines, (ent-10, 48, 70) and chiral enamino esters (52, 55, 73) with maleic anhydride (32), citraconic anhydride (57), a-chloroacrylonitrile (29), and nitroethylene (74), has been investigated. ... -
Etude pharmacologique de fractions antidiabétiques de feuilles d'Icacina oliviformis (Poiret) Raynal
Manga, Anastasie; Gassama, Abdoulaye; Fall, A. D.; Diatta, K.; Diatta, W.; Sy, Gata Yoro; Bassène, Emmanuel (2013)Icacina oliviformis (Poiret) Raynal est une plante de la pharmacopée traditionnelle sénégalaise dont les feuilles sont utilisées au Sénégal dans le traitement du diabète. L’extraction de la poudre de feuilles a été faite ... -
Evaluation of In Vitro Antiplasmodial Activity of Icacina oliviformis’s (Stems and Roots) and Spondias Purpurea’s (Leaves, Barks And Roots) Extracts from Ziguinchor, Senegal
Gassama, Abdoulaye; Diatta, Armel; Sambou, Oumar; Manga, Anastasie; Cojean, Sandrine; Cavé, Christian (2019)This study was designed to assess phytochemical and antiplasmodial activities of Icacina oliviformis’s and Spondias purpurea’s extracts. Icacina oliviformis (poiret) Raynal (Icacinaceae) and Spondias purpurea L. (Anacardiaceae) ... -
Étude chimique et pharmacologique des fractions anti-hyperglycémiantes des fibres de la noix de Cocos nucifera L. (Arecaceae) de Ziguinchor, Sénégal
Gassama, Abdoulaye; Manga, Anastasie; Diatta, Armel; Bassène, Emmanuel; Sy, Gata Yoro; Lavaud, Catherine (2018)Cocos nucifera L. (Arecaceae) est une plante de la pharmacopée traditionnelle sénégalaise, dont les fibres sont utilisées au Sénégal dans le traitement du diabète. Afin de prouver et de valoriser l’activité antidiabétique ... -
Faidherbia albida Del. (Leguminosae), is a plant of the Senegal traditional pharmacopoeia whose leaves and bark are used in the treatment of various diseases. Investigation on Faidherbia albida Del. resulted in the isolation two glycosyl flavones 1 and 2. The isolated compounds were characterized by NMR and mass-spectrometry. The present study constitutes the first phytochemical examination of the barks of Faidherbia albida Del.
Diatta, Armel; Manga, Anastasie; Gassama, Abdoulaye; Lavaud, Catherine (2017)Spondias purpurea L. (Anacardiaceae) est une plante de la pharmacopée traditionnelle sénégalaise, dont les feuilles sont utilisées dans le traitement de diverses maladies. L’extrait éthalonique des feuilles a présenté ... -
Flavonoïds isolated from barks of Faidherbia albiba (Delile) A. Chev
Karé, Moussa; Lô, Cheikh; Boulanger, Anna; Gassama, Abdoulaye (2022)Faidherbia albida Del. (Leguminosae), is a plant of the Senegal traditional pharmacopoeia whose leaves and bark are used in the treatment of various diseases. Investigation on Faidherbia albida Del. resulted in the isolation ...