Browsing UFR des Sciences et Technologies (ST) by Subject "Reductive amination"

Now showing items 1-3 of 3

    • Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives 

      Seck, Rokhyatou; Gassama, Abdoulaye; Cojean, Sandrine; Cavé, Christian (2020)
      In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and with a less side-effects, we have designed and synthesized a library of 1,4-disubstituted piperidine derivatives from 4-aminopiperidine ...

    • Synthesis of 1,2,3-triazole containing derivative of peperidine 

      Thiam, Aminata; Seck, Rokhyatou; Camara, Magatte; Sambou, Oumar; Diatta, Armel; Gassama, Abdoulaye (2020)
      A reductive amination reaction between N-Boc -piperidin-4-one and phenoxy-ethylamine was successfully used for the synthesis of (5-Methyl-2-phenyl-2H-[1,2,3] triazol-4ylmethyl)- (2-phenoxy-ethyl)-piperidin-4-yl-amine. The ...

    • Synthesis of N-Substituted piperidines from piperidone 

      Gassama, Abdoulaye; Diatta, Armel (2015)
      A reductive amination reaction between N-boc-piperidin-4-one and 3,4-dichloroaniline was successfully employed for the synthesis of the N-(3,4-dichloropheny)-N-(2-phenoxylethyl) piperidin-4-amine. The synthesis of a small ...