| dc.description.abstract | Spondias purpurea L. (Anacardiaceae) is a Senegalese traditional
pharmacopoeia plant, which leaves are used in the treatment of various
diseases. The leaves’ ethanolic extract exhibited antihyperglycemic activity
on models of temporary hyperglycemia. The tests were performed on
normoglycemic rats with a glucose tolerance test. The phytochemical
investigation of the leaves resulted in the isolation of four flavonoids
(quercetin 9, kaempferol 10, quercetin-3- ß-glucopyranoside 6, kaempferol3-ß-galactopyranoside 8), five phenolic compounds (2,4-dihydroxybenzoic
acid 2, 4-hydroxybenzoic acid 5, protocatechic 4-ß-glucoside acid 1,
hydroxycynnamic acid 7, 5-caffeoylquinic acid 3) and one tannin (Strictinin
4). The known isolated compounds were characterized by NMR and massspectrometry. The present study constitutes the first phytochemical
examination of the leaves and the anti-hyperglycemic activity of the
ethanolic extract of Spondias Purpurea L. | en_US |
