Browsing by Author "Mansaly, Malamine"
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Synthesis and antimalarial activity of cinnamic acid derivatives
Seck, Rokhyatou; Mansaly, Malamine; Gassama, Abdoulaye; Cavé, Christian; Cojean, Sandrine (2019)A peptide coupling reaction between 1-(R)-phenylethylalanine and cinnamic acid derivatives has been successfully employed for the synthesis of a set of small molecules. The antimalarial activity of these derivative molecules ... -
Synthesis and evaluation of the antimalarial activity of cinnamic acids derived from piperidine
Seck, Rokhyatou; Mansaly, Malamine; Gassama, Abdoulaye; Cavé, Christian; Cojean, Sandrine (2019)The synthesis and antimalarial activity of 1, 4-aminopiperidine derived cinnamic acids are described. Different analogs are prepared from reductive amination reactions and SN1 substitutions. These analogs are tested ...