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Asymmetric synthesis of glutamate derivatives
(2017)
Analogs of glutamic acid were synthesized through the asymmetric Michael reaction using chiral acyclic
E-enaminoesters and various Michael acceptors. The influence of the alkoxy group of the enaminoesters and
also the ...
Synthesis and antimalarial activity of cinnamic acid derivatives
(2019)
A peptide coupling reaction between 1-(R)-phenylethylalanine and cinnamic acid derivatives has been
successfully employed for the synthesis of a set of small molecules. The antimalarial activity of these derivative
molecules ...
Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives
(2020)
In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and
with a less side-effects, we have designed and synthesized a library of 1,4-disubstituted piperidine
derivatives from 4-aminopiperidine ...
Synthesis and evaluation of the antimalarial activity of cinnamic acids derived from piperidine
(2019)
The synthesis and antimalarial activity of 1, 4-aminopiperidine derived cinnamic acids are described. Different
analogs are prepared from reductive amination reactions and SN1 substitutions. These analogs are tested ...
Synthesis of 1,2,3-triazole containing derivative of peperidine
(2020)
A reductive amination reaction between N-Boc -piperidin-4-one and phenoxy-ethylamine was successfully used
for the synthesis of (5-Methyl-2-phenyl-2H-[1,2,3] triazol-4ylmethyl)- (2-phenoxy-ethyl)-piperidin-4-yl-amine.
The ...