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Antiplasmodial activity of extracts of Khaya senegalensis (Ders.) A. Jus (Meliaceae) and Melia azedarach L., plants of senegalese traditional medecine
(2018)
Two medicinal plants (Khaya senegalensis and Melia azedarach),
frequently used by a large part of the Senegalese population and in particular
that of the natural region of Casamance in the traditional treatment of ...
Antiplasmodial activity of the ethanolic extract of icacina oliviformis (STEMS), spondias purpurea L.(leaves, barks and roots) and cocos nucifera L. (coconut shell fibers) from Ziguinchor, Senegal
(2018)
Icacina oliviformis (poiret) Raynal (Icacinaceae), Spondias purpurea L. (Anacardiaceae) and Cocos nucifera L.
(Arecaceae) are Senegalese traditional pharmacopoeia plants used in the treatment of various diseases. These
plants ...
Enantioselective acces to five- and six- membered nitogen - containing heterocycles, based on the asymetric Michael addition of chiral imines and chiral enamino esters.
(1998)
The addition reaction of chiral imines, (ent-10, 48, 70) and chiral enamino esters (52, 55, 73) with maleic anhydride (32), citraconic anhydride (57), a-chloroacrylonitrile (29), and nitroethylene (74), has been investigated. ...
Asymmetric synthesis of glutamate derivatives
(2017)
Analogs of glutamic acid were synthesized through the asymmetric Michael reaction using chiral acyclic
E-enaminoesters and various Michael acceptors. The influence of the alkoxy group of the enaminoesters and
also the ...
Regioselective Annulation of 1,5-Diketones: Access to Functionalized Hagemann’s Esters
(European Journal of Organic Chemistry, 2000)
The synthesis of the ‘‘functionalized’’ Hagemann’s ester (S)-
18 was investigated. The common starting material in these
approaches was enamino ester (S,Z)-5, which was prepared
through the condensation of keto diester ...
Synthesis and antimalarial activity of cinnamic acid derivatives
(2019)
A peptide coupling reaction between 1-(R)-phenylethylalanine and cinnamic acid derivatives has been
successfully employed for the synthesis of a set of small molecules. The antimalarial activity of these derivative
molecules ...
Evaluation of In Vitro Antiplasmodial Activity of Icacina oliviformis’s (Stems and Roots) and Spondias Purpurea’s (Leaves, Barks And Roots) Extracts from Ziguinchor, Senegal
(2019)
This study was designed to assess phytochemical and antiplasmodial activities of Icacina oliviformis’s and Spondias purpurea’s
extracts. Icacina oliviformis (poiret) Raynal (Icacinaceae) and Spondias purpurea L. (Anacardiaceae) ...
Synthesis and Antimalarial Activity of 1,4-Disubstituted Piperidine Derivatives
(2020)
In order to prepare, at low cost, new compounds active against Plasmodium falciparum, and
with a less side-effects, we have designed and synthesized a library of 1,4-disubstituted piperidine
derivatives from 4-aminopiperidine ...
Synthesis and evaluation of the antimalarial activity of cinnamic acids derived from piperidine
(2019)
The synthesis and antimalarial activity of 1, 4-aminopiperidine derived cinnamic acids are described. Different
analogs are prepared from reductive amination reactions and SN1 substitutions. These analogs are tested ...
Condensation of Chiral lmines and Chiral ]]-Enaminoesters with Maleic and Citraconic Anhydrides
(1997)
Condenmlions of chiral imines I and 4, and chiral ennminoesters 10 and 13. ~ ma/e~ and
citracoaic anhydrides were reported. These experimen:al om~com~ can be ratio _l~__~ed by invaking the
compact, eado-aplaroaches of ...